HP1 gamma Rabbit Monoclonal Antibody-EnkiLife

HP1 gamma Rabbit Monoclonal Antibody

Summary

Production Name	HP1 gamma Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC,IP
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purification

Immunogen

Gene Name	CBX3
Alternative Names	CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein
Gene ID	11335
SwissProt ID	Q13185

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50
Molecular Weight	Calculated MW: 21 kDa; Observed MW: 21 kDa

Background

Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Research Area

Epigenetics and Nuclear Signaling