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Dlx5 (19R2) Rabbit Monoclonal Antibody

Dlx5 (19R2) Rabbit Monoclonal Antibody

Cat: AMRe10029
Size:50μL Price:$128
Size:100μL Price:$230
Size:200μL Price:$380
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:DLX5 Category: 組換えモノクローナル抗体 Tags:

Summary

Production Name

Dlx5 (19R2) Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

DLX5

Alternative Names

Distal less homeo box 5; Dlx 5; Homeo box protein DLX 5;

Gene ID

1749

SwissProt ID

P56178

 

Application

Dilution Ratio

WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:500-1:1000

Molecular Weight

32kDa

 

Background

Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.

 

Research Area

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