RHXF1_HUMAN Q8NHV9
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UniProt:Q8NHV9
Recommended name:Rhox homeobox family member 1
EC number:
Alternative names:(Ovary-, testis- and epididymis-expressed gene protein) (Paired-like homeobox protein PEPP-1)
Cleaved into:
GeneID:158800
Gene names (primary ):RHOXF1
Gene names (synonym ):OTEX PEPP1
Gene names (ORF ):
Length:184
Mass:20542
Sequence:MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHENGMNRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRADPDDCVYIVVD
Tissue specificity:Ovary, testis and epididymis. Also detected in the prostate and the mammary gland. Expressed in many tumor cell lines derived from acute lymphocytic leukemia, prostate, endometrial adenocarcinoma, melanoma, bladder carcinoma, colon carcinoma, erythroleukemia and breast carcinoma. Not expressed in placenta. In testis, mainly expressed in germ cells, but also detected in somatic cells such as Sertoli cells, Leydig cells and peritubular cells (PubMed:28171660). {ECO:0000269|PubMed:12490318, ECO:0000269|PubMed:28171660}.
Induction:By androgen.
Developmental stage:Predominantly expressed in late stage germ cells, pachytene spermatocytes and round spermatides. {ECO:0000269|PubMed:28171660}.
Protein families:Paired-like homeobox family, PEPP subfamily