SF3B3 Rabbit Monoclonal Antibody-EnkiLife

SF3B3 Rabbit Monoclonal Antibody

Summary

Production Name	SF3B3 Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,ICC/IF
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purification

Immunogen

Gene Name	SF3B3
Alternative Names	SF3B3; KIAA0017; SAP130; Splicing factor 3B subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; SF3b130; STAF130; Spliceosome-associated protein 130; SAP 130
Gene ID	23450
SwissProt ID	Q15393

Application

Dilution Ratio	WB 1:500-1:1000,ICC/IF 1:50-1:200
Molecular Weight	Calculated MW: 136 kDa; Observed MW: 136 kDa

Background

Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.

Research Area

Epigenetics and Nuclear Signaling