Summary
Performance
Immunogen
Application
Background
E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.
Research Area
Neuroscience
Summary
| Production Name | Phospho-MDM2 (Ser166) Rabbit Monoclonal Antibody |
| Description | Recombinant rabbit monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC |
| Reactivity | Human,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Phosphorylated |
| Isotype | IgG |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Purification | Affinity Purification |
Immunogen
| Gene Name | MDM2 |
| Alternative Names | Double minute 2 protein; Hdm2; Oncoprotein Mdm2 |
| Gene ID | 4193 |
| SwissProt ID | Q00987 |
Application
| Dilution Ratio | WB 1:500-1:1000,IHC 1:50-1:100 |
| Molecular Weight | Calculated MW: 55 kDa; Observed MW: 90 kDa |
Background
E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.
Research Area
Neuroscience