KIF5B Rabbit Monoclonal antibody-EnkiLife

KIF5B Rabbit Monoclonal antibody

Summary

Production Name	KIF5B Rabbit Monoclonal antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC,ICC/IF,IP
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purified

Immunogen

Gene Name	KIF5B
Alternative Names	KNS; KINH; KNS1; UKHC; HEL-S-61
Gene ID	3799
SwissProt ID	P33176

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight	Calculated MW: 110 kDa; Observed MW: 110 kDa

Background

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner . Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation .

Research Area

Signal Transduction