Summary
Performance
Immunogen
Application
Background
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.
Research Area
