DDB1 Rabbit Monoclonal Antibody-EnkiLife

DDB1 Rabbit Monoclonal Antibody

Summary

Production Name	DDB1 Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC,ICC/IF,IP
Reactivity	Human,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purification

Immunogen

Gene Name	DDB1
Alternative Names	XPE; DDBA; XAP1; XPCE; XPE-BF; UV-DDB1
Gene ID	1642
SwissProt ID	Q16531

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight	Calculated MW: 127 kDa; Observed MW: 127 kDa

Background

Required for DNA repair. Binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair.

Research Area

Epigenetics and Nuclear Signaling